Emerging pathogens Laboratory

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Research themes

FMX website

https://www.fondation-merieux.org/en/what-we-do/enhancing-research-capabilities/research-laboratories/emerging-pathogens-laboratory/

Our laboratory in Lyon-Gerland runs collaborative research programs and boosts the careers of scientists in developing countries.

The Emerging Pathogens Laboratory conducts research with applications in the fields of global health and infectious diseases that affect vulnerable populations in developing countries and during outbreaks.

Located in Lyon-Gerland, at the hub for infectious disease research on the Charles Mérieux Campus, our Emerging Pathogens Laboratory has two main areas of focus:

  • Develop and transfer technologies for the diagnosis and epidemiological surveillance of infectious diseases,
  • Support the careers of researchers in developing countries through partnerships, collaborative programs, and training courses.

Our laboratory team is comprised of researchers, technicians, and PhD students, working in BSL2 and BSL3 laboratory zones, with access to the BSL4 category P4 Jean Mérieux-Inserm Laboratory and the technology platforms at SFR128 BioSciences Gerland-Lyon Sud.

A member of major scientific networks

The Emerging Pathogens Laboratory, whose scientific team is a member of the International Center for Infectiology Research (CIRI), belongs to several scientific networks of excellence:

  • AVIESAN (French National Alliance for Life Sciences and Health)
  • ISARIC (International Severe Acute Respiratory and Emerging Infection Consortium)
  • The European Union’s HORIZON 2020 research programs: COMPARE, GloPID-R and ZikaPLAN
  • The European EVAg Consortium (European Virus Archive global), funded by the European Union

GABRIEL website

Laboratory

http://gabriel.dev.globe-network.org/laboratoires/emerging-pathogens-laboratory/?lang=en

The Emerging Pathogens Laboratory (EPL) has been part of the Scientific Committee of the Fondation Mérieux since January 2011.

The team is made up of 12 staff members including 8 researchers, 1 bioinformatician, 1 technician, and 2 administrative assistants.

The Emerging Pathogens Laboratory, covering a surface area of 450m2 and subdivided into offices and laboratories, is located near the Jean Mérieux BSL-4 laboratory on the Charles Mérieux campus in Lyon, in a stimulating academic environment for the study of virology and immunology. The EPL operates its own BSL-2 laboratory, and has access to a BSL-3 laboratory for research on MDR-TB and viral pathogens requiring containment.  In addition, through collaboration with the Institute of Biomedical Research of the French Army (IRBA), we conduct research on Crimean-Congo Hemorrhagic fever virus in the BSL-4 laboratory.

Since January 2013, the EPL has been one of the units collaborating with the International Center for Research on Infectious Diseases (CIRI), which was created to federate health care institutions from the Charles Mérieux campus involved in collaborative research projects on infectious diseases.

Its main mission is to strengthen local clinical biology and applied research capacities for a better understanding of infectious diseases.

Research Activities

http://gabriel.dev.globe-network.org/laboratoires/emerging-pathogens-laboratory/research-activities/?lang=en

Applied research has the following main areas of activities:

  • Identification of bioMarkers in respiratory infections
  • Epidemiology of respiratory infections
  • TB multidrug resistance identification
  • Surveillance for antimicrobial resistance
  • Emerging viral infections

 

One of the missions is to develop new diagnostic tools for emerging pathogens for developing countries. Another mission is to provide training and technical support to the GABRIEL network laboratories located in the developing countries. The group has several years of experience in molecular and cell biology and protein biochemistry.

The EPL is involved in several public health programmes for which it proposes diagnostic solutions, and conducts applied and operational research to evaluate how introduction of novel diagnostic tools can contribute to improved disease control and prevention.

The EPL conducts research to characterize biodiversity of viral and bacterial pathogens, and monitor the appearance of resistance to treatments (tuberculosis, influenza) or spread in previously unaffected populations (arboviruses).

The team has built an international network of reseach collaborations in UK, Switzerland, France, The Netherlands and Brazil. The hemorrhagic fever programme is carried out in collaboration with the French Army Health Service.

The Emerging Pathogens Laboratory is also member of the LabEx Ecofect ‘Eco-Evolutionary Dynamics of Infectious Diseases’.

Team Presentation

http://gabriel.dev.globe-network.org/laboratoires/emerging-pathogens-laboratory/team-presentation/?lang=en

 

Scientific publications

http://gabriel.dev.globe-network.org/laboratoires/emerging-pathogens laboratory/publications/?lang=en

 

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