Molecular basis of viral pathogenicity

Afficher tout

Selected publications

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE Jr, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM.
Cell. 2018;174(4):938-952.e13

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG. Pyankov OV, Setoh YX, Bodnev SA, Edmonds JH, Pyankova OG, Pyankov SA, Pali G, Belford S, Lu L, La M, Lovrecz G, Volchkova VA, Chappell KJ, Watterson D, Marsh G, Young PR, Agafonov AA, Farmer JF, Volchkov VE, Suhrbier A, Khromykh AA.
Sci Rep. 2017; 7:41537.

RNA Editing of the GP Gene of Ebola Virus is an Important Pathogenicity Factor. Volchkova VA, Dolnik O, Martinez MJ, Reynard O, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S226-33.

Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity. Dolnik O, Volchkova VA, Escudero-Perez B, Lawrence P, Klenk HD, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S322-8.

Ebola Virus GP Gene Polyadenylation Versus RNA Editing. Volchkova VA, Vorac J, Repiquet-Paire L, Lawrence P, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S191-8.

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability. Escudero-Pérez B, Volchkova VA, Dolnik O, Lawrence P, Volchkov VE.
PLoS Pathog. 2014; 10(11): e1004509.

Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1. Page A, Volchkova VA, Reid SP, Mateo M, Bagnaud-Baule A, Nemirov K, Shurtleff AC, Lawrence P, Reynard O, Ottmann M, Lotteau V, Biswal SS, Thimmulappa RK, Bavari S, Volchkov VE.
Cell Rep. 2014 Mar 27;6(6):1026-36. doi: 10.1016/j.celrep.2014.02.027.

Structure of Nipah virus unassembled nucleoprotein in complex with its viral chaperone. Yabukarski F, Lawrence P, Tarbouriech N, Bourhis JM, Delaforge E, Jensen MR, Ruigrok RW, Blackledge M, Volchkov V, Jamin M.
Nat Struct Mol Biol. 2014 Sep;21(9):754-9. doi: 10.1038/nsmb.2868.

Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses. Jones SM, Feldmann H, Stroher U, Geisbert JB, Fernando L, Grolla A, Klenk HD, Sullivan NJ, Volchkov VE, Fritz EA, Daddario KM, Hensley LE, Jahrling PB, Geisbert TW.
Nat Med. 2005, 11(7), 720-721.

Ectodomain shedding of the glycoprotein GP of Ebola virus. Dolnik O, Volchkova V, Garten W, Carbonnelle C, Becker S, Kahnt J, Ströher U, Klenk H-D, Volchkov V.
EMBO J. 2004; 23, 2175-2184.

Recovery of infectious Ebola virus from cDNA: RNA editing of the GP gene and viral cytotoxicity. Volchkov VE, Volchkova VA, Mühlberger E, Kolesnikova LV, Weik M, Dolnik O, Klenk HD.
Science. 2001; 291 (5510): 1965-1969.

Crystal structure of the matrix protein VP40 from Ebola virus. Dessen A, Volchkov V, Dolnik O, Klenk HD, Weissenhorn W.
EMBO J. 2000; 19: 4228-4236.

Human asymptomatic Ebola infection and strong inflammatory response. Leroy EM, Baize S, Volchkov VE, Fisher-Hoch SP, Georges-Courbot MC, Lansoud-Soukate J, Capron M, Debre P, McCormick JB, Georges AJ.
Lancet. 2000; 355: 2210-2215.

Brevets

  •  Peptides including a binding domain of the viral phosphoprotein (P) subunit to the viral RNA free nucleoprotein (N°). PCT/EP2015/066419/13390029US.
  •  Antibodies specific to Glycoprotein (GP) of Ebola virus and uses for the treatment and diagnosis of Ebola virus infection. Europe and US patent EP15305348.3/ US 62/113,597.

 

Publications (since 2008)

High Pathogenicity Nipah Virus from Pteropus lylei Fruit Bats, Cambodia.
Gaudino M, Aurine N, Dumont C,Fouret J, Ferren M, Mathieu C , Reynard O, Volchkov VE, Legras-Lachuer C, Georges-Courbot MC, Horvat B.
Emerg Infect Dis. 2020 Jan;26(1):104-113.

Involvement of Surfactant Protein D in Ebola Virus Infection Enhancement via Glycoprotein Interaction.
Favier AL, Reynard O, Gout E, van Eijk M, Haagsman HP, Crouch E, Volchkov V, Peyrefitte C, Thielens NM.
Viruses. 2019 Jan; 11(1): 15.

Taxonomy of the order Mononegavirales: update 2018.
Amarasinghe GK, Aréchiga Ceballos NG, Banyard AC, Basler CF, Bavari S, Bennett AJ, Blasdell KR, Briese T, Bukreyev A, Caì Y, Calisher CH, Campos Lawson C, Chandran K, Chapman CA, Chiu CY, Choi KS, Collins PL, Dietzgen RG, Dolja VV, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Echevarría JE, Fooks AR, Formenty PBH, Fouchier RAM, Freuling CM, Ghedin E, Goldberg TL, Hewson R, Horie M, Hyndman TH, Jiāng D, Kityo R, Kobinger GP, Kondō H, Koonin EV, Krupovic M, Kurath G, Lamb RA, Lee B, Leroy EM, Maes P, Maisner A, Marston DA, Mor SK, Müller T, Mühlberger E, Ramírez VMN, Netesov SV, Ng TFF, Nowotny N, Palacios G, Patterson JL, Pawęska JT, Payne SL, Prieto K, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Siddell S, Smither SJ, Song Q, Song T, Stenglein MD, Stone DM, Takada A, Tesh RB, Thomazelli LM, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Vázquez-Morón S, Verdugo C, Volchkov VE, Wahl V, Walker PJ, Wang D, Wang LF, Wellehan JFX, Wiley MR,, Whitfield AE, Wolf YI, Yè G, Zhāng YZ, Kuhn JH.
Arch Virol. 2018 Aug;163(8):2283-2294.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.
Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE Jr, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM.
Cell. 2018;174(4):938-952.e13.

Mannoside Glycolipid Conjugates Display Antiviral Activity Against Ebola Virus.
Reynard O, Schaeffer E, Volchkova VA, Cimarelli A, Mueller CG, Volchkov VE.
J Infect Dis. 2018;218 (suppl 5):S666-S671. doi: 10.1093/infdis/jiy464.

Interference with the production of infectious viral particles and bimodal inhibition of replication are broadly conserved antiviral properties of IFITMs.
Tartour K, Nguyen XN, Appourchaux R, Assil S, Barateau V, Bloyet LM, Burlaud Gaillard J, Confort MP, Escudero-Perez B, Gruffat H, Hong SS, Moroso M, Reynard O, Reynard S, Decembre E, Ftaich N, Rossi A, Wu N, Arnaud F, Baize S, Dreux M, Gerlier D, Paranhos-Baccala G, Volchkov V, Roingeard P, Cimarelli A.
PLoS Pathog. 2017 Sep; 28;13(9):e1006610. doi: 10.1371/journal.ppat.1006610.

Taxonomy of the order Mononegavirales: update 2017
Amarasinghe GK, Bào Y, Basler CF, Bavari S, Beer M, Bejerman N, Blasdell KR, Bochnowski A, Briese T, Bukreyev A, Calisher CH, Chandran K, Collins PL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Fang Q, Formenty P, Fouchier RAM, Ghedin E, Harding RM, Hewson R, Higgins CM, Hong J, Horie M, James AP, Jiāng D, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lee B, Leroy EM, Li M, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Pearson MN, Randall RE, Revill PA, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Smither SJ, Song Q, Stone DM, Takada A, Terregino C, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang B, Wang D, Wang F, Wang LF, Werren JH, Whitfield AE, Yan Z, Ye G, Kuhn JH.
Arch Virol. 2017;162(8):2493-2504. doi: 10.1007/s00705-017-3311-7.

Implementation of Objective PASC-Derived Taxon Demarcation Criteria for Official Classification of Filoviruses.
Bào Y, Amarasinghe GK, Basler CF, Bavari S, Bukreyev A, Chandran K, Dolnik O, Dye JM, Ebihara H, Formenty P, Hewson R, Kobinger GP, Leroy EM, Mühlberger E, Netesov SV, Patterson JL, Paweska JT, Smither SJ, Takada A, Towner JS, Volchkov VE, Wahl-Jensen V, Kuhn JH.
Viruses. 2017, 11;9(5). pii: E106. doi: 10.3390/v9050106.

Successful post-exposure prophylaxis of Ebola infected non-human primates using Ebola glycoprotein-specific equine IgG.
Pyankov OV, Setoh YX, Bodnev SA, Edmonds JH, Pyankova OG, Pyankov SA, Pali G, Belford S, Lu L, La M, Lovrecz G, Volchkova VA, Chappell KJ, Watterson D, Marsh G, Young PR, Agafonov AA, Farmer JF, Volchkov VE, Suhrbier A, Khromykh AA.
Sci Rep. 2017; 7:41537.

Possibility and Challenges of Conversion of Current Virus Species Names to Linnaean Binomials.
Postler TS, Clawson AN, Amarasinghe GK, Basler CF, Bavari S, Benko M, Blasdell KR, Briese T, Buchmeier MJ, Bukreyev A, Calisher CH, Chandran K, Charrel R, Clegg CS, Collins PL, Juan Carlos T, Derisi JL, Dietzgen RG, Dolnik O, Dürrwald R, Dye JM, Easton AJ, Emonet S, Formenty P, Fouchier RAM, Ghedin E, Gonzalez JP, Harrach B, Hewson R, Horie M, Jiang D, Kobinger G, Kondo H, Kropinski AM, Krupovic M, Kurath G, Lamb RA, Leroy EM, Lukashevich IS, Maisner A, Mushegian AR, Netesov SV, Nowotny N, Patterson JL, Payne SL, PaWeska JT, Peters CJ, Radoshitzky SR, Rima BK, Romanowski V, Rubbenstroth D, Sabanadzovic S, Sanfaçon H, Salvato MS, Schwemmle M, Smither SJ, Stenglein MD, Stone DM, Takada A, Tesh RB, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Volchkov VE, Wahl-Jensen V, Walker PJ, Wang LF, Varsani A, Whitfield AE, Zerbini FM, Kuhn JH.
Syst Biol. 2017 May 1;66(3):463-473. doi: 10.1093/sysbio/syw096.

Taxonomy of the order Mononegavirales: update 2016.
Afonso CL, Amarasinghe GK, Bányai K, Bào Y, Basler CF, Bavari S, Bejerman N, Blasdell KR, Briand FX, Briese T, Bukreyev A, Calisher CH, Chandran K, Chéng J, Clawson AN, Collins PL, Dietzgen RG, Dolnik O, Domier LL, Dürrwald R, Dye JM, Easton AJ, Ebihara H, Farkas SL, Freitas-Astúa J, Formenty P, Fouchier RA, Fù Y, Ghedin E, Goodin MM, Hewson R, Horie M, Hyndman TH, Jiāng D, Kitajima EW, Kobinger GP, Kondo H, Kurath G, Lamb RA, Lenardon S, Leroy EM, Li CX, Lin XD, Liú L, Longdon B, Marton S, Maisner A, Mühlberger E, Netesov SV, Nowotny N, Patterson JL, Payne SL, Paweska JT, Randall RE, Rima BK, Rota P, Rubbenstroth D, Schwemmle M, Shi M, Smither SJ, Stenglein MD, Stone DM, Takada A, Terregino C, Tesh RB, Tian JH, Tomonaga K, Tordo N, Towner JS, Vasilakis N, Verbeek M, Volchkov VE, Wahl-Jensen V, Walsh JA, Walker PJ, Wang D, Wang LF, Wetzel T, Whitfield AE, Xiè JT, Yuen KY, Zhang YZ, Kuhn JH.
Arch Virol. 2016 Aug;161(8):2351-60. doi: 10.1007/s00705-016-2880-1.

Enhancement of Ebola Virus Infection via Ficolin-1 Interaction with the Mucin Domain of GP Glycoprotein.
Favier AL, Gout E, Reynard O, Ferraris O, Kleman JP, Volchkov V, Peyrefitte C, Thielens NM.
J Virol. 2016; 90(11):5256-69.

Anti-EBOV GP IgGs Lacking α1-3-Galactose and Neu5Gc Prolong Survival and Decrease Blood Viral Load in EBOV-Infected Guinea Pigs. 
Reynard O, Jacquot F, Evanno G, Mai HL, Salama A, Martinet B, Duvaux O, Bach JM, Conchon S, Judor JP, Perota A, Lagutina I, Duchi R, Lazzari G, Le Berre L, Perreault H, Lheriteau E, Raoul H, Volchkov V, Galli C, Soulillou JP.
PLoS One. 2016; 11(6):e0156775.

Ebola Virus GP Gene Polyadenylation Versus RNA Editing.
Volchkova VA, Vorac J, Repiquet-Paire L, Lawrence P, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S191-8.

Entry of Ebola Virus is an Asynchronous Process.
Reynard O, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S199-203.

Shedding of Ebola Virus Surface Glycoprotein Is a Mechanism of Self-regulation of Cellular Cytotoxicity and Has a Direct Effect on Virus Infectivity.
Dolnik O, Volchkova VA, Escudero-Perez B, Lawrence P, Klenk HD, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S322-8.

RNA Editing of the GP Gene of Ebola Virus is an Important Pathogenicity Factor.
Volchkova VA, Dolnik O, Martinez MJ, Reynard O, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S226-33.

Characterization of a Novel Neutralizing Monoclonal Antibody Against Ebola Virus GP.
Reynard O, Volchkov VE.
J Infect Dis. 2015; 212 Suppl 2:S372-8.

A Kunjin replicon virus-like particle vaccine provides protection against Ebola virus infection in nonhuman primates.
Pyankov OV, Bodnev SA, PyankovaOG, Solodkyi VV, Pyankov SA, Setoh YH, Volchkova VA, Suhrbier A, Volchkov VE, Agafonov AA, Khromykh AA,
J Infect Dis. 2015; 212 Suppl 2:S368-71.

Identification of a New Ribonucleoside Inhibitor of Ebola Virus Replication.
Reynard O, Nguyen XN, Alazard-Dany N, Barateau V, Cimarelli A, Volchkov VE.
Viruses. 2015; 7(12): 6233-40.

Virus nomenclature below the species level: a standardized nomenclature for filovirus strains and variants rescued from cDNA.
Kuhn JH, Bào Y, Bavari S, Becker S, Bradfute S, Brauburger K, Rodney Brister J, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Hoenen T, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Volchkova VA, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST.
Arch Virol. 2014; 159(5):1229-37.

Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability.
Escudero-Pérez B, Volchkova VA, Dolnik O, Lawrence P, Volchkov VE.
PLoS Pathog 2014; 10(11): e1004509.

Structure of Nipah virus unassembled nucleoprotein in complex with its viral chaperone.
Yabukarski F, Lawrence P, Tarbouriech N, Bourhis JM, Delaforge E, Jensen MR, Ruigrok RW, Blackledge M, Volchkov V, Jamin M.
Nat Struct Mol Biol. 2014 Sep;21(9):754-9. doi: 10.1038/nsmb.2868.

A first outbreak of Ebola virus in West Africa.French
Reynard O, Volchkov V, Peyrefitte C.
Med Sci (Paris). 2014 Jun-Jul;30(6-7):671-3. doi: 10.1051/medsci/20143006018.

Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1.
Page A, Volchkova VA, Reid SP, Mateo M, Bagnaud-Baule A, Nemirov K, Shurtleff AC, Lawrence P, Reynard O, Ottmann M, Lotteau V, Biswal SS, Thimmulappa RK, Bavari S, Volchkov VE.
Cell Rep. 2014 Mar 27;6(6):1026-36. doi: 10.1016/j.celrep.2014.02.027.

Surface glycoproteins of the recently identified African Henipavirus promote viral entry and cell fusion in a range of human, simian and bat cell lines.
Lawrence P, Escudero Pérez B, Drexler JF, Corman VM, Müller MA, Drosten C, Volchkov V.
Virus Res. 2014 Mar 6;181:77-80. doi: 10.1016/j.virusres.2014.01.003

Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae.
Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Caì Y, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Gonzalez JP, Formenty P, Freiberg AN, Hensley LE, Honko AN, Ignatyev GM, Jahrling PB, Johnson KM, Klenk HD, Kobinger G, Lackemeyer MG, Leroy EM, Lever MS, Lofts LL, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Ryabchikova EI, Saphire EO, Shestopalov AM, Smither SJ, Sullivan NJ, Swanepoel R, Takada A, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Warfield KL, Weidmann M, Nichol ST.
Arch Virol. 2013 Jun;158(6):1425-32. doi: 10.1007/s00705-012-1594-2.

Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae.
Kuhn JH, Bao Y, Bavari S, Becker S, Bradfute S, Brister JR, Bukreyev AA, Chandran K, Davey RA, Dolnik O, Dye JM, Enterlein S, Hensley LE, Honko AN, Jahrling PB, Johnson KM, Kobinger G, Leroy EM, Lever MS, Mühlberger E, Netesov SV, Olinger GG, Palacios G, Patterson JL, Paweska JT, Pitt L, Radoshitzky SR, Saphire EO, Smither SJ, Swanepoel R, Towner JS, van der Groen G, Volchkov VE, Wahl-Jensen V, Warren TK, Weidmann M, Nichol ST.
Arch Virol. 2013 Jan;158(1):301-11. doi: 10.1007/s00705-012-1454-0.

Nonstructural Nipah virus C protein regulates both the early host proinflammatory response and viral virulence.
Mathieu C, Guillaume V, Volchkova VA, Pohl C, Jacquot F, Looi RY, Wong KT, Legras-Lachuer C, Volchkov VE, Lachuer J, Horvat B.
J Virol. 2012 Oct;86(19):10766-75. doi: 10.1128/JVI.01203-12.

Ebola virus failure to stimulate plasmacytoid dendritic cell interferon responses correlates with impaired cellular entry.
Leung LW, Martinez O, Reynard O, Volchkov VE, Basler CF.
J Infect Dis. 2011 Nov;204 Suppl 3:S973-7. doi: 10.1093/infdis/jir331.

Genomic RNA editing and its impact on Ebola virus adaptation during serial passages in cell culture and infection of guinea pigs.
Volchkova VA, Dolnik O, Martinez MJ, Reynard O, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S941-6. doi: 10.1093/infdis/jir321.

Role of VP30 phosphorylation in the Ebola virus replication cycle.
Martinez MJ, Volchkova VA, Raoul H, Alazard-Dany N, Reynard O, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S934-40. doi: 10.1093/infdis/jir320.

Knockdown of Ebola virus VP24 impairs viral nucleocapsid assembly and prevents virus replication.
Mateo M, Carbonnelle C, Martinez MJ, Reynard O, Page A, Volchkova VA, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S892-6. doi: 10.1093/infdis/jir311.

Conserved proline-rich region of Ebola virus matrix protein VP40 is essential for plasma membrane targeting and virus-like particle release.
Reynard O, Nemirov K, Page A, Mateo M, Raoul H, Weissenhorn W, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S884-91. doi: 10.1093/infdis/jir359.

Unconventional secretion of Ebola virus matrix protein VP40.
Reynard O, Reid SP, Page A, Mateo M, Alazard-Dany N, Raoul H, Basler CF, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S833-9. doi: 10.1093/infdis/jir305.

Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection.
Reynard O, Mokhonov V, Mokhonova E, Leung J, Page A, Mateo M, Pyankova O, Georges-Courbot MC, Raoul H, Khromykh AA, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S1060-5. doi: 10.1093/infdis/jir347.

VP24 is a molecular determinant of Ebola virus virulence in guinea pigs.
Mateo M, Carbonnelle C, Reynard O, Kolesnikova L, Nemirov K, Page A, Volchkova VA, Volchkov VE.
J Infect Dis. 2011 Nov;204 Suppl 3:S1011-20. doi: 10.1093/infdis/jir338.

Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry.
Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH.
J Virol. 2011 Sep;85(17):8502-13. doi: 10.1128/JVI.02600-10.

The human metapneumovirus matrix protein stimulates the inflammatory immune response in vitro.
Bagnaud-Baule A, Reynard O, Perret M, Berland JL, Maache M, Peyrefitte C, Vernet G, Volchkov V, Paranhos-Baccalà G.
PLoS One. 2011 Mar 11;6(3):e17818. doi: 10.1371/journal.pone.0017818.

Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations.
Kuhn JH, Becker S, Ebihara H, Geisbert TW, Johnson KM, Kawaoka Y, Lipkin WI, Negredo AI, Netesov SV, Nichol ST, Palacios G, Peters CJ, Tenorio A, Volchkov VE, Jahrling PB.
Arch Virol. 2010 Dec;155(12):2083-103. doi: 10.1007/s00705-010-0814-x.

Mutations abrogating VP35 interaction with double-stranded RNA render Ebola virus avirulent in guinea pigs.
Prins KC, Delpeut S, Leung DW, Reynard O, Volchkova VA, Reid SP, Ramanan P, Cárdenas WB, Amarasinghe GK, Volchkov VE, Basler CF.
J Virol. 2010 Mar;84(6):3004-15. doi: 10.1128/JVI.02459-09.

Ebolavirus VP24 binding to karyopherins is required for inhibition of interferon signaling.
Mateo M, Reid SP, Leung LW, Basler CF, Volchkov VE.
J Virol. 2010 Jan;84(2):1169-75. doi: 10.1128/JVI.01372-09.

Ebolavirus glycoprotein GP masks both its own epitopes and the presence of cellular surface proteins.
Reynard O, Borowiak M, Volchkova VA, Delpeut S, Mateo M, Volchkov VE.
J Virol. 2009 Sep;83(18):9596-601. doi: 10.1128/JVI.00784-09.

Nipah virus sequesters inactive STAT1 in the nucleus via a P gene-encoded mechanism.
Ciancanelli MJ, Volchkova VA, Shaw ML, Volchkov VE, Basler CF.
J Virol. 2009 Aug;83(16):7828-41. doi: 10.1128/JVI.02610-08.

Nipah virus edits its P gene at high frequency to express the V and W proteins.
Kulkarni S, Volchkova V, Basler CF, Palese P, Volchkov VE, Shaw ML.
J Virol. 2009 Apr;83(8):3982-7. doi: 10.1128/JVI.02599-08.

Role of Ebola virus VP30 in transcription reinitiation.
Martínez MJ, Biedenkopf N, Volchkova V, Hartlieb B, Alazard-Dany N, Reynard O, Becker S, Volchkov V.
J Virol. 2008 Dec;82(24):12569-73. doi: 10.1128/JVI.01395-08.