Forum d’infectiologie: Pr. Fernando MACIAN JUAN

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Date / Heure
Date(s) - 01/12/2017
11 h 00 min - 12 h 00 min

Amphi Pasteur, Tour CERVI

Pr. Fernando MACIAN JUAN (Albert Einstein College of Medicine Dpt of Pathology and Institute for Aging Research Bronx – NY – USA): «Regulation of T cell responses by distinct forms of autophagy »

Fernando MACIAN JUAN has more than 20 years of experience in the study and characterization of the molecular mechanisms that regulate T cell activation and tolerance. His group has pioneered the identification and characterization of the signaling pathways, transcriptional complexes and molecular events that regulate the functional outcome following T cell receptor engagement in peripheral T cells. His studies have contributed to the identification of the transcriptional and signaling events that regulate T cell fate upon antigen encounter and determine T helper cell differentiation, activation and tolerance. In the last 10 years, his group has helped defined the roles and regulation of different forms of autophagy in T cell biology and has contributed to the establishment of autophagy as an essential cell process in the modulation of T helper cell responses

contact: Mathias Faure